Symptom-centric view

Osteonecrosis

Substances reporting Osteonecrosis disproportionately — ranked by ROR.

Pain Drug ineffective Off label use Fatigue Dyspnoea Acute kidney injury

showing 26 of 26

Substance ↓	ROR [95% CI]	Reports	Category	Label
zoledronic acid —	17.4 [16.3–18.5]	1,028	algemeen	new
thioguanine —	15.7 [11.9–20.7]	51	algemeen	new
thalidomide —	7.9 [7.2–8.7]	451	algemeen	new
tenofovir disoproxil fumarate —	176.0 [171.8–180.4]	11,043	algemeen	new
tenofovir alafenamide —	164.5 [159.9–169.2]	7,124	algemeen	new
tamoxifen citrate —	15.4 [13.0–18.2]	136	algemeen	new
rilpivirine hydrochloride —	118.3 [112.5–124.4]	1,887	algemeen	new
rilpivirine —	56.2 [53.6–59.0]	1,898	algemeen	new
pamidronate disodium —	119.9 [109.3–131.6]	536	algemeen	new
nelfinavir mesylate —	20.7 [16.2–26.4]	67	algemeen	new
lopinavir and ritonavir —	11.9 [10.5–13.5]	251	algemeen	new
imiglucerase —	11.6 [9.3–14.4]	84	algemeen	new
emtricitabine, rilpivirine hydrochloride, and tenofovir disoproxil fumarate —	189.5 [178.7–200.9]	1,507	algemeen	new
emtricitabine, rilpivirine hydrochloride, and tenofovir alafenamide —	158.9 [146.2–172.7]	706	algemeen	new
emtricitabine and tenofovir disoproxil fumarate —	220.2 [214.6–226.0]	9,687	algemeen	new
emtricitabine and tenofovir alafenamide —	184.4 [179.1–189.9]	6,691	algemeen	new
emtricitabine —	153.1 [149.4–156.8]	10,911	algemeen	new
elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate —	204.8 [194.7–215.3]	2,101	algemeen	new
elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide —	212.1 [202.3–222.4]	2,385	algemeen	new
darunavir, cobicistat, emtricitabine, and tenofovir alafenamide —	181.7 [165.8–199.2]	598	algemeen	new
darunavir ethanolate and cobicistat —	22.3 [17.2–28.8]	60	algemeen	new
darunavir —	29.6 [27.6–31.8]	838	algemeen	new
cobicistat —	173.0 [166.9–179.4]	4,047	algemeen	new
bictegravir sodium, emtricitabine, and tenofovir alafenamide fumarate —	164.3 [158.0–170.9]	3,370	algemeen	new
atazanavir —	9.5 [8.3–10.8]	215	algemeen	new
abacavir sulfate, dolutegravir sodium, lamivudine —	11.5 [9.6–13.9]	114	algemeen	new

ROR = reporting odds ratio vs. the full FAERS corpus. A signal is not a cause. Source: openFDA (FAERS).